![]() If your pancreas doesn’t make enough bicarbonate (a substance that lowers the acid level in your small intestine), your pH level may be too acidic, which prevents the enzymes from working properly. Your small intestine needs to have a certain pH level, meaning the environment cannot be too acidic. Why am I still experiencing malabsorption or losing weight after I started on my enzymes?Ī few things could cause your enzymes to not work effectively. If you are consistently forgetting to take your enzymes you may notice you are losing weight, have a change in your stool, or have excessive gas or pain after eating. You may derive some benefit if you take your enzymes towards the end of the meal if you forgot to take them initially, however this is not ideal. If you forget to take your enzymes and only remember after you are done eating, it may not help to take them at that point. It is important that you do not store your enzymes in a warm place such as your pocket or in direct sunlight, as this can cause the medication to become ineffective. The enzymes should be effective for up to one hour so if you eat later than one hour after taking your enzymes, you will need to take another dose. I recommend taking the entire dose directly before your meal, or with your first bite of food. How should they be taken?Īlways take your enzymes as directed by your provider. As you can see, this is a large range and you need to work closely with your provider to assure you are taking the right amount. ![]() This would be between 1-5 pills per meal of the largest available dose, 36,000. As an example of what an appropriate dose range would be, for an adult weighing 150 pounds, a range 34,100 – 170,500 units of lipase per meal is appropriate. Most people take the 24,000 dosed pills, but some people find them too large to swallow and prefer to take smaller pills. Depending upon the brand, enzyme dosages vary. Additionally, half of the meal dosage should be taken with snacks. Enzymes are often dosed between 500-2500 units of lipase per kilogram (kg) per meal. The enzymes are dosed off of the units of lipase (the enzyme that digests fat) and they come in different doses, depending on the brand. These are all signs of malabsorption, which means you may not be making enough pancreatic enzymes to digest your food and could benefit from taking pancreatic enzymes. Most people only experience one or two symptoms. You may want to discuss with your doctor if you notice any of the following: yellow, floating, or greasy stools or diarrhea, excessive gas, painful cramping after eating, or weight loss despite eating your usual amount of food. If you have a medical problem affecting your pancreas that does not necessarily mean you need to take pancreatic enzymes. If you need to take pancreatic enzymes, you should only take those prescribed by your doctor. Health stores sell over the counter enzymes as well, but these are not FDA regulated and the amount of enzymes they contain may differ from what is advertised. There are six FDA approved pancreatic enzymes, which are available by prescription only: Creon, Pancreaze, Zenpep, Ultresa, Viokace, and Pertzye. ![]() Some of these problems include, but are not limited to, pancreatic cancer, large pancreatic cysts, chronic pancreatitis, long-term use of a medication called Sandostatin, or cystic fibrosis. Certain medical problems can cause your pancreas to produce fewer enzymes than needed for digestion. Pancreatic enzymes are pills that help you digest food. In this post, she answers frequently asked questions about the benefits and proper use of pancreatic enzymes. Deborah Gerszberg, RD, CNSC, CDN, Clinical Nutritionist at The Pancreas Center, writes regularly about nutritional issues for patients with pancreatic cancer, pancreatitis, and other pancreatic diseases, which commonly cause problems with eating or maintaining their weight. ![]()
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